Surfing The Medical AI Tsunami
Why the Deepest Waters Hold the Greatest Opportunity
The AI tsunami isn't like other technological revolutions. Most innovations improve existing processes—steam engines made transportation faster, computers made calculations quicker, the internet made information more accessible. But artificial intelligence is different. It's not enhancing human capabilities; it's creating new forms of intelligence that can perceive patterns, generate insights, and solve problems in ways that human cognition simply cannot match.
This is a displacement event. Like geological tsunamis that permanently reshape coastlines, the AI tsunami is redrawing the fundamental landscape of human knowledge work. And just like surfers who study wave formations to position themselves optimally, entrepreneurs and professionals must understand the deeper dynamics of this transformation to choose their position wisely.
This wave is massive and comprehensive—it's hitting every industry simultaneously with transformational force. Unlike previous technological revolutions that moved through the economy sector by sector over decades, AI is restructuring all knowledge work at once. The question isn't which industries will be affected or when—it's where you choose to position yourself within this universal transformation.
The Physics of AI Waves
Real tsunamis gain power from underwater topography. In deep ocean waters, they're barely noticeable. But as they approach shallow coastal areas, they slow down, build height, and unleash tremendous force. The AI tsunami follows similar physics, but the "depth" isn't geographical—it's informational.
AI waves are most powerful where three conditions converge: massive information density, complex pattern recognition requirements, and high-stakes decision making. These create the informational equivalent of deep underwater terrain that allows AI to build transformational force.
Shallow Waters: Process optimization, content generation, customer service automation. Important applications, but the underlying problems are relatively straightforward. AI provides efficiency gains, but the fundamental nature of the work doesn't change. Competition is fierce because barriers to entry are low.
Medium Depth: Financial analysis, legal research, supply chain management. More complex pattern recognition, but within well-defined parameters. AI creates significant advantages, but human expertise remains central. Multiple players can succeed because the solution space is broad.
Deep Waters: Drug discovery, climate modeling, quantum computing, precision medicine. Here, AI doesn't just improve existing approaches—it enables entirely new methods of understanding complex systems. The information density is so high, the pattern recognition requirements so complex, that human cognition hits fundamental limits.
Why Healthcare Represents the Deepest Waters
Healthcare sits at the perfect convergence of the three factors that create maximum AI wave power:
Information Density: Healthcare generates more complex, multi-dimensional data than any other field. A single cancer patient's genomic profile contains 3 billion data points. Medical imaging produces millions of pixels per scan. Electronic health records capture thousands of variables over decades. This isn't just big data—it's impossibly complex data that exceeds human analytical capacity.
Pattern Recognition Complexity: Medical decision-making requires integrating patterns across genetic, molecular, cellular, physiological, and behavioral levels simultaneously. The interaction effects are non-linear and often counterintuitive. A mutation that's benign in one genetic context can be lethal in another. Treatment responses depend on hundreds of variables that no human mind can simultaneously process.
High Stakes: Healthcare decisions directly determine life and death outcomes. The cost of being wrong isn't just financial—it's measured in years of life lost, families destroyed, human potential unrealized. This creates both the urgent need for AI's superior pattern recognition and the willingness to invest heavily in solutions that work.
Most importantly, healthcare is the last major industry still operating under pre-AI assumptions about human cognitive limits. We practice medicine designed for what doctors can remember, analyze, and decide—not for what's actually possible with available information.
The Precision Oncology Wave
Within healthcare's deep waters, precision oncology represents the deepest point—where the informational tsunami builds maximum force. Cancer is simultaneously the most complex disease (every tumor is genetically unique) and the most data-rich (comprehensive genomic, proteomic, and therapeutic response databases). It's where human cognitive limitations create the largest gap between theoretical possibility and clinical reality.
Traditional oncology treats cancer by organ site and stage—lung cancer, breast cancer, stage III, stage IV. But cancer's true nature is genetic. A KRAS-mutated lung cancer has more in common biologically with a KRAS-mutated colon cancer than with other lung cancers. The genetic fingerprint, not the anatomical location, determines which treatments will work.
This creates an extraordinary opportunity for AI. Where human oncologists can consider perhaps a dozen variables when selecting treatment, AI can simultaneously analyze complete genomic profiles, protein expression patterns, immune signatures, treatment response data from thousands of similar cases, and real-time resistance predictions. It's not incremental improvement—it's a qualitative leap to a new form of medical intelligence.
Why the Deepest Waters Create the Strongest Competitive Moats
Choosing the deepest waters isn't just about impact—it's about building advantages that become stronger over time rather than weaker.
Data Network Effects: In precision oncology, every patient outcome makes the AI system smarter. The company that treats the most patients develops the most sophisticated understanding of which genetic profiles respond to which treatments. This creates a compounding advantage—success attracts more patients, which generates more data, which improves outcomes, which attracts even more patients.
Complexity Barriers: The technical challenges of analyzing multi-dimensional genomic data, predicting treatment responses, and integrating thousands of research papers aren't just difficult—they require sustained investment in specialized AI talent, proprietary datasets, and clinical partnerships. These barriers protect genuine innovation from being quickly copied.
Regulatory Moats: Healthcare AI requires FDA approval pathways, clinical validation, and integration with major medical centers. Companies that successfully navigate these requirements first establish relationships and track records that are difficult for followers to replicate.
Human Capital Scarcity: Building AI for precision oncology requires teams that understand both cutting-edge machine intelligence and deep cancer biology. This intersection of expertise is extremely rare, creating natural limits on how many companies can effectively compete.
The Strategic Choice
Every entrepreneur faces the same fundamental choice: where to position themselves as the AI tsunami reshapes the economy. This isn't just about choosing a market—it's about choosing the informational depth where you want to build.
The strategic insight is this: the same factors that make deep water dangerous—technical complexity, high barriers to entry, regulatory requirements, long development cycles—are exactly what protect genuine innovation from commoditization.
In the deepest informational waters, AI doesn't just improve existing approaches—it enables entirely new methods of understanding complex systems that were previously beyond human cognitive reach.
Riding the Deepest Wave
I've chosen to build CureWise in precision oncology not despite its complexity, but because of it. The technical challenges that scare away some entrepreneurs are exactly what will create sustainable competitive advantages. The regulatory hurdles that seem daunting are what will protect our innovations from being quickly replicated. The clinical validation requirements that appear burdensome are what will establish trust with the medical community.
Most importantly, precision oncology is where AI's capabilities can create the most profound human impact. When our AI correctly predicts which treatment will work for a specific patient's unique cancer, we're not optimizing a business process—we're giving someone years or decades more life with their family.
The informational density of cancer genomics, the pattern recognition complexity of treatment selection, and the life-or-death stakes of oncology decisions create the perfect conditions for AI to demonstrate its transformational potential. This isn't just about building a better tool—it's about enabling a new form of medicine that was previously impossible.
The Exponential Reality
The AI transformation isn't following a predictable timeline where you can wait for clearer signals or better positioning. This is exponential change—where capabilities that seem impossible today become routine tomorrow, and the gap between leaders and followers expands at an accelerating rate.
We're living through months that feel like years of progress. GPT-4 capabilities that amazed us in early 2023 already feel quaint compared to what's emerging. AI systems are discovering new antibiotics, proving mathematical theorems, and generating insights that human researchers couldn't conceive. The acceleration isn't slowing—it's compounding.
In exponential change, there is no "window closing" because there's no way to predict what becomes possible next week, next month, or next year. The only certainty is that waiting for clarity means falling exponentially behind those who are building now.
The choice isn't whether to ride the AI wave—it's coming whether you're ready or not. The choice is where to position yourself: in shallow waters where the risks are lower but the opportunities are limited, or in deep waters where the challenges are greatest but the potential for breakthrough impact is unlimited.
I've made my choice. I'm building where the water is deepest, where AI's capabilities can create the most profound value, where the technical challenges create the strongest competitive moats. In precision oncology, where every patient's unique genetic fingerprint becomes the map to their cure.
The tsunami is here. The waves are building. Choose your depth wisely.
Steve Brown
Founder & CEO, CureWise
Building the future where cancer becomes personally and precisely curable.


"The genetic fingerprint, not the anatomical location, determines which treatments will work." That statement is true to a certain degree. The human body, under siege by cancer, is more than just a genetic blueprint that responds to pharmaceutical manipulation. It is a complex web of interactive organ systems, each of which contributes to the success or failure of an anti-cancer regimen. Research indicates that if the microbiome exhibits specific imbalances, checkpoint inhibitors for cancer may be less effective or ineffective. Suppose CureWise is to be most effective for all who enter data. In that case, it must take into account the imbalances that exist in each organ system and consider effective therapies for those systems, if the anti-cancer regimen recommended is to work for everyone. Toxin overload (exogenous or endogenous), micronutrient deficiency, systemic inflammation, and uncontrolled stress responses are just a few examples. Best of luck with the ingenious program!